The 22-year-old centre-back came up the ranks at Usuthu and has featured 10 times for the senior side since his breakthrough in the 2025/26 season.
Despite not yet featuring for AmaZulu this season, the young centre-back is highly rated and expected to fight for a place in the Sundowns squad.
Sundowns announced news of the signing on their social media accounts, penning: "Mamelodi Sundowns have added another young talent to the roster! Yellow Nation, let's welcome Wandile Dube to the Yellow army.
"Wandile Dube joins the Yellow Family.
"A new face joins the ranks. Wandile Dube officially becomes a part of Bafana Ba Style."
