The Buccaneers lifted last season's MTN8 trophy with a comprehensive 3-0 victory over Stellenbosch.
They face a Durban City side, who last season won the Nedbank Cup, and who are now under the guidance of former Kaizer Chiefs co-coach Khalil Ben Youssef.
The match will take place at the Amstel Orlando Arena on Saturday, ahead of Mamelodi Sundowns' clash with Polokwane City at the Lucas Moripe Stadium.
Kaizer Chiefs, meanwhile, host Golden Arrows at the FNB Stadium on Sunday and AmaZulu host Sekhukhune United at the Chatsworth Stadium on Sunday.
Ahead of their game, Bucs boss Abdeslam Ouaddou said that's important for his team to win the MTN8 again this season.
He said on iDiski Times: "[Reaching the MTN8 final] is one very important moment in my starting of coaching Orlando Pirates.
"Of course, a lot of people are expecting that game and the club has been winning that competition. [Winning it] is the target for me, for the players and for the club but let me tell you that the club has many targets this season.
“And we cannot only focus on that moment [the final], it's one moment that is very important but it's the moment that is such important as the other ones – the league, other cups as well as the [CAF] Champions League. We will try definitely to give our best and make our fans happy.”
