The Buccaneers secured their last four place with a last-gasp 3-2 extra-time win over Durban City.
Babina Noko, meanwhile, overcame AmaZulu after a seven-goal thriller with a 4-3 victory.
Elsewhere, Mamelodi Sundowns beat Polokwane City 3-2 to set up a semi-final clash with Golden Arrows after they edged Kaizer Chiefs 1-0 on Sunday.
Full list of semi-final fixtures:
Sekhukhune United v Orlando Pirates
Mamelodi Sundowns v Golden Arrows
